Centro Hospitalar Lisboa Norte

Serviço de Reumatologia

Informação Geral

Direção

Diretor do Serviço: Prof. Doutor João Eurico Cabral da Fonseca

Administrador Hospitalar: Dra. Patrícia Gonçalves

 

Enfermeira: Enf.ª Lurdes Narciso 

Secretária da Direção do Serviço: Sandra Guimarães

Coordenadores da Consulta de Reumatologia: Dr. Carlos Miranda Rosa e Dra. Carla Macieira

Coordenador da Unidade de Internamento de Reumatologia: Dr. José Carlos Romeu

Coordenador da Unidade de Técnicas de Reumatologia: Dr. Fernando Saraiva

Coordenadora do Hospital de Dia de Reumatologia: Dra. Mª João Saavedra

Coordenadora da Unidade de Reumatologia Pediátrica: Dra. Filipa Oliveira Ramos

Coordenador da Unidade de Doenças Ósseas Metabólicas: Dr. José Carlos Romeu

Coordenadora da Unidade de Ensaios Clínicos de Reumatologia: Dra. Elsa Vieira de Sousa

 

Contactos

Secretariado: 217805139 

Email: Este endereço de email está protegido contra piratas. Necessita ativar o JavaScript para o visualizar.

Enfermaria: 217805558

Hospital de Dia de Reumatologia: 217805439

Unidade de Técnicas de Reumatologia: 217805000 ext: 53263

 

Horário

Horário Funcionamento Serviços administrativos:

• Consulta Reumatologia: 2ª a 6ª feira, das 8h às 20h

• Unidade de Internamento de Reumatologia: 2ª a 6ª feira, das 8h às 16h 

• Unidade de Técnicas de Reumatologia: 2ª a 6ª feira, das 8h às 20h 

• Hospital de Dia de Reumatologia: 2ª a 6ª feira, das 8h às 20h

• Unidade de Doenças Ósseas Metabólicas: 2ª a 6ª feira, 8h às 20h

• Unidade de Reumatologia Pediátrica: 2ª a 6ª feira, 8h às 18h

• Unidade de Ensaios Clínicos de Reumatologia: 2ª a 6ª feira, das 8h às 16.30h

 

Localização

Direção e Secretariado da Direção do Serviço: piso 7 – Elevador 7, 18 ou 19

Consultas de Reumatologia: piso 1, Centro de Ambulatório (algumas Hospital Pulido-Valente)

Hospital de Dia de Reumatologia: piso 1

Unidade de Técnicas de Reumatologia: piso 1, junto ao Centro de Ambulatório

Unidade de Internamento: sectores A, B, C e D do internamento do Serviço de Medicina 2, piso 3, - Elevador 12

Unidade de Reumatologia Pediátrica: consultas - pavilhão da consulta externa de Pediatria, piso 1; técnicas de reumatologia pediátrica - Unidade de Técnicas de Pediatria, piso 1; internamento e hospital de dia – Departamento de Pediatria

Unidade de Ensaios Clínicos - Centro de Investigação Clínica, piso 7, elevador 6

 

Recursos Humanos

Categoria

Número

Assistente Hospitalar Graduado

8

Assistente Hospitalar

10

Internos de Formação Específica

13

Enfermeiros

1

Assistente Técnico

1

Assistente Operacional

1

 

Equipa Médica

 

Ana Antunes Valido

Ana Filipa B. L. Oliveira Ramos

Ana Rita Da Cruz Machado

Ana Teresa Melo

Carla Marina C. M. S. Pinheiro

Carlos António Miranda Rosa

Catarina Isabel M. O. L. Resende

Catarina Tenazinha

Cristina Dias Botelho da Ponte

Eduardo Dourado

Elsa Cristina Vieira Sousa

Fernando Manuel Diamantino Saraiva

Inês Cordeiro

Joana da Silva Marques Coelho Dinis

João Eurico C. Cabral da Fonseca

Joaquim Miguel Polido Pereira

José Carlos M. Santos Romeu

Luís Manuel Bravo Gaião

Maria João Gonçalves Martins

Maria João Rego Saavedra

Mário Jorge Trol Bexiga

Nikita Khmelinskii

Patrícia Martins

Pedro Manuel Ávila Ribeiro

Raquel Patrícia Campanilho Marques

Rita Alexandra Rebelo Cardoso de Oliveira Barros

Rui Pedro Lourenço Teixeira

Sofia Carvalho Fernandes Barreira

Susana Paula L D Abreu Capela

Vasco Madeira C. Romão

História do Serviço

Com origem em 1977, o então Núcleo de Reumatologia do Serviço de Medicina IV, foi criado pelo Prof. Doutor Mário Viana de Queiroz e pelo Prof. Doutor Fernando de Pádua, Diretor daquele Serviço. Em 1980 o Núcleo de Reumatologia viu reconhecida, pela Ordem dos Médicos, a idoneidade para formação de Reumatologistas. Em 1981 recebe os primeiros internos de Reumatologia por Concurso de Ingresso no Internato Complementar. 

A sua atividade assistencial teve, praticamente desde o seu início, 3 unidades funcionais principais: a Consulta Externa, onde logo na primeira metade dos anos 80 se individualizaram as Consultas de Doenças Ósseas Metabólicas e de Reumatologia Pediátrica e, mais tarde, a de Doenças Reumáticas Inflamatórias, a Unidade de Internamento dedicada, mas não em exclusividade, ao internamento de doentes reumáticos, e a Unidade de Técnicas. A assistência reumatológica aos doentes internados em outros Serviços do Hospital constituiu igualmente uma das principais atividades do Núcleo. 

O Núcleo de Reumatologia sempre desenvolveu uma intensa atividade formativa, quer na formação de internos de reumatologia e de outras especialidades em estágio formativo no Núcleo, quer na participação e organização de Cursos, Jornadas, Simpósios, Congressos e outras  Reuniões Científicas de formação pós-graduada, e na edição de livros sobre reumatologia. Da mesma forma, acompanha a história do Serviço uma marcante atividade de investigação e uma ligação contínua ao ensino pré-graduado.

O Núcleo de Reumatologia  deu origem ao Serviço de Reumatologia e Doenças Ósseas Metabólicas, criado em junho de 2003 no âmbito da departamentalização do Hospital de Santa Maria.

Ao longo destes 14 últimos anos, até aos dias de hoje, muitas foram as mudanças estruturais do Hospital que influenciaram o funcionamento do Serviço de Reumatologia. As mudanças com mais impacto ocorreram com a construção de um espaço comum multidisciplinar de Consultas (Centro de Ambulatório) e a criação dos espaços no piso 1 para o Hospital de Dia de Reumatologia e a Unidade de Técnicas de Reumatologia.

Atividade Assistencial

Atividade Assistencial

a) Consulta externa de Reumatologia

  • Consulta de Artrite Psoriática (conjunta com dermatologia)
  • Consulta de Artrite Reumatóide
  • Consulta de Artrites Iniciais
  • Consulta de Dietética e Nutrição de Reumatologia
  • Consulta de Doenças Ósseas Metabólicas
  • Consulta de Doenças Reumáticas na Gravidez (conjunta com obstetrícia)
  • Consulta de Doenças Reumáticas de início Juvenil 
  • Consulta de Esclerose Sistémica 
  • Consulta de Espondilartrites e Uveítes
  • Consulta de Hipertensão Pulmonar de doenças Reumáticas (conjunta com cardiologia e pneumologia
  • Consulta de Lúpus Eritematoso Sistémico
  • Consulta de Mini-artroscopia
  • Consulta de Miosites (conjunta com dermatologia e medicina física e reabilitação)
  • Consulta de Osteoartrose e Artrites Microcristalinas
  • Consulta de Psicologia
  • Consulta de Reumatologia Geral
  • Consulta de Síndrome de Sjogren (conjunta com estomatologia e oftalmologia)
  • Consulta de Triagem
  • Consulta de Vasculites
  • Consulta Multidisciplinar de Reumatologia/Anatomia Patológica
  • Consulta Multidisciplinar de Reumatologia/Imagiologia
  • Consulta Multidisciplinar Reumatologia/Dermatologia
  • Consulta Multidisciplinar Reumatologia/Oftalmologia em idade adulta
  • Consulta Multidisciplinar Reumatologia/Ortopedia
  • Consulta Pré-concepcional de Doenças Reumáticas (conjunta com obstetrícia)

 

b) Unidade de Internamento de Reumatologia

  • Internamento de doentes reumáticos 
  • Apoio a doentes reumáticos internados noutros serviços
  • Consulta pós alta

 

c) Unidade de Técnicas de Reumatologia

  • Artrocentese
  • Biópsia gordura subcutânea abdominal
  • Biópsia glândulas salivares 
  • Biópsia sinovial guiada por ecografia 
  • Capilaroscopia
  • Ecografia do aparelho locomotor
  • Infiltração epidural
  • Infiltração periarticular
  • Infiltração intra-articular (sinoviortese)
  • Lavagem articular
  • Mesoterapia
  • Microscopia de luz polarizada
  • Mini-artroscopia
  • Osteodensitometria
  • Procedimentos diagnósticos ecoguiados
  • Procedimentos terapêuticos Ecoguiados
  • Procedimentos terapêuticos Radioguiados
  • Teste de patergia

 

d) Hospital de Dia de Reumatologia

  • Consulta de decisão de início de terapêuticas biológicas
  • Consulta de vigilância da eficácia e da segurança das terapêuticas biológicas
  • Administração de terapêuticas endovenosas
  • Ensino e administração de terapêuticas subcutâneas

 

e) Unidade de Reumatologia Pediátrica 

  • Apoio de Reumatologia Pediátrica aos doentes internados no Departamento de Pediatria
  • Consulta de Doenças Auto-inflamatórias (conjunta com imunodeficiencias e genética)
  • Consulta de Doenças Reumáticas de início juvenil
  • Consulta de Reumatologia Pediátrica
  • Consulta de Transição de Reumatologia Pediátrica para Reumatologia de Adultos
  • Consulta Multidisciplinar Reumatologia Pediátrica/Medicina Física e Reabilitação Pediátrica
  • Consulta Multidisciplinar Reumatologia Pediátrica/Oftalmologia Pediátrica
  • Períodos dedicados a Doentes Pediátricos no Hospital de Dia de Reumatologia
  • Técnicas de diagnóstico e terapêutica de Reumatologia Pediátrica na Unidade de Técnicas de Pediatria

 

f) Unidade de Doenças Ósseas Metabólicas

  • Consulta Externa dedicada a osteoporose estabelecida (fracturária) e/ou secundária, doença óssea de Paget, adultos com alterações crónicas do metabolismo mineral e/ou pertubações crónicas da mineralização óssea , adultos com osteogénese imperfeita, osteopetrose e outras displasias  ósseas raras  
  • Consultadoria para Centro de Referência para a Área da Paramiloidose Familiar do Hospital de Santa Maria/CHLN
  • Consultadoria para o Centro de Referência para a Área das Doenças Hereditárias do Metabolismo do Hospital de Santa Maria/CHLN
  • Avaliação de Densidade Mineral  Óssea (Densitometria Óssea na Unidade de Técnicas de Reumatologia)
  • Avaliação de composição corporal por Densitometria Radiológica de Dupla Energia (DXA)  em âmbito de investigação clínica
  • Acessibilidade a terapêuticas específicas, incluindo respectivo ensino de administração subcutânea ou administração  em Hospital de Dia de Reumatologia     

g) Unidade de Ensaios Clínicos de Reumatologia 

  • Colaboração no desenvolvimento do Centro de Investigação Clínica
  • Planeamento de ensaios clínicos de iniciativa do investigador
  • Implementação no Serviço de ensaios clínicos multicêntricos  de fase I, II, III e IV
  • Seleção de doentes candidatos aos ensaios clínicos
  • Consultas e tratamentos associados a ensaios clínicos
  • Formação e treino em ensaios clínicos

 

Lista de ensaios clínicos em curso

 

Nome do Ensaio Clínico

R4RA
A randomised, open labelled study in anti-TNFa inadequate responders to investigate the mechanisms for Response - Resistance to Rituximab versus Tocilizumab in RA

SEAM RA STUDY
A Randomized Withdrawal Double-blind Study of Etanercept Monotherapy Compared to Methotrexate Monotherapy for Maintenance of Remission in Subjects With Rheumatoid Arthritis  

EARLY
A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 Once Daily Monotherapy to Methotrexate (MTX) Monotherapy in MTX-Naïve Subjects with Moderately to Severely Active Rheumatoid Arthritis

MONOTHERAPY
A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 Monotherapy to Methotrexate (MTX) in Subjects with Moderately to Severely Active Rheumatoid Arthritis with Inadequate Response to MTX

BEYOND
A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 to Placebo on Stable Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs) in Subjects with Moderately to Severely Active Rheumatoid Arthritis with Inadequate Response or Intolerance to Biologic DMARDs (bDMARDs)

GLORIA
The Glucocorticoid Low-dose Outcome in Rheumatoid Arthritis. Comparing the cost-effectiveness and safety of additional low-dose glucocorticoid in treatment strategies for elderly patients with rheumatoid arthritis

MEASURE
A randomized, double-blind, placebo-controlled pahse III multicenter study of secukinumab to demonstrate the efficacy at 16 weeks and to assess the long-term safety, tolerability and efficacu up to 3 years in subjects with active Ankylosing Spondylitis

PREVENT
A randomized, double-blind, placebo-controlled multicenter study of secukinumab to demonstrate the efficacy at 16 weeks and to assess the long term safety, tolerability and efficacy up to 2 years in patients with active nonradiographic axial spondyloarthritis.

PROOF
Patients with axial Spondyloarthritis: Multi-country registry of clinical characteristics, including radiographic progression, and burden of disease over 5 years in real-life setting

GO-DACT 
A multicentre, randozmized, double-blind, parallel-group study to compares the efficacy of golimumab in combination with methotrexate (MTX) versus MTX monotherapy, in improving dactylitis and enthesitis, in MTX naive psoriatic arthritis patients

SEAM PSA
STUDY A Multicenter Double-Blind, Randomized Controlled Study of Etanercept and Methotrexate in Combination or as Monotherapy in Subjects With Psoriatic Arthritis .  

BASE
A Randomized, Double-Blind Placebo-Controlled 52-Week Study to Assess Adverse Events of Special Interest in Adults with Active, Autoantibody-Positive Systemic Lupus Erythematosus Receiving Belimumab

LUPIL-2
A Phase II, multi-centre, randomized, double blind, placebo-controlled study to evaluate the efficacy, safety and pharmacokinetics of ILT-101 in patients with active moderate to severe systemic lupus erythematosus

BI 1293.10
A double-blind, randomised, placebo-controlled trial evaluating the effect of three doses of BI 655064 administered weekly as sub-cutaneneous injections, on renal response after one year treatment, in patients with active lupus nephritis

SÖURCE
A multi-center randomized, double-blind, placebo-controlled, parallel group study to assess the efficacy of RG7625 in patients with primary Sjögren’s syndrome

 

Atividade Formativa

O Serviço de Reumatologia é um espaço de promoção de formação, atualização e inovação do conhecimento médico. 

Atividade Formativa:

  • Atividade formativa pré-graduada: colaboração no ensino nas disciplinas de Bioquímica, Anatomia e Histologia do Mestrado Integrado de Engenharia Biomédica, Doenças do Aparelho Locomotor, Introdução à Clínica, Opção de Reumatologia, Práticas Clínicas Tutoriais de Reumatologia e Medicina II. Colaboração em programas de intercâmbio. 
  • Atividade formativa pós-graduada: formação de internos de formação específica de Reumatologia (cerca de 12 em permanência), formação de internos de Medicina Geral e Familiar, de Medicina Física e de Reabilitação, e de Medicina Interna. Formação de internos provenientes de outros países europeus, Brasil e países africanos de expressão oficial portuguesa.
  • Actividade Formativa interna do Serviço: promove reuniões semanais para discussão de temas, protocolos de actuação, recomendações e projectos de investigação. Colabora em acções de formação organizadas por Sociedades Científicas. Promove as CAML Rheumatology Series.

 

Atividade Investigacional

Atividade Investigacional

O Serviço de Reumatologia desenvolve uma atividade intensa de investigação em diversas áreas da Reumatologia em colaboração estreita com a Unidade de Investigação em Reumatologia do Instituto de Medicina Molecular da Faculdade de Medicina da Universidade de Lisboa. 

Projetos a decorrer no Serviço de Reumatologia/Unidade de Investigação em Reumatologia 

  • Estudo Prognóstico da Arterite Temporal / PROgnosis of TEmporal Arteritis Study (PROTEA)
  • Is ultrasound a good surrogate marker for remission in RA? (Association of ultrasound and histological synovitis in rheumatoid arthritis patients in clinical remission).
  • Blood biomarkers of synovial tissue phenotype as predictors of response to TNF inhibitors and tocilizumab in rheumatoid arthritis
  • IL-6-blockade in rheumatoid arthritis patients: impact on Tfh subsets and its relation to treatment response
  • Avaliação Eficácia e Segurança Zoledronato a longo Prazo na Doença Óssea de Paget
  • Evaluation of celastrol as a candidate for the treatment of rheumatoid arthritis
  • B cells in Juvenile Idiopathic Arthritis
  • Síndromes autoinflamatórios – análise nacional com base na Reuma.pt
  • Ensaio clínico de mesoterapia
  • Outcomes na idade adulta da Artrite Idiopática Juvenil
  • Avaliação clínica, analítica, radiológica e ecográfica de doentes com artrite em fase inicial
  • Loss of follow up dos doentes sob Biológicos
  • The role of lncRNAs in Rheumatoid Arthritis-associated bone degradation
  • Serum sphingolipids as candidate biomarkers in Rheumatoid Arthritis
  • Systemic Sclerosis Clinical Study (SSPECT)
  • Predictors of response to ultrasound-guided sacroiliac joint corticosteroid-injection in patients  with active sacroiliitis
  • Paget’s disease of bone (PDB) – Contribution to the study of its pathogenesis
  • Clinical Outcomes of African Patients drom Portuguese Speaking Countries Evacuated for Medical Assessment in Portugal– Rheumatology as a case study
  • Protocolo de Actuação na Nefropatia Lúpica
  • Predictors of radiographic progression in Psoriatic Arthritis patients
  • Tapering biologics in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
  • Long term effect of tofacitinib on bone: friend or foe?
Informação atualizada em Agosto de 2017 

 

Abaixo encontram-se listadas as publições dos últimos 5 anos:

2012

Canhão H, Rodrigues AM, Mourão AF, Martins F, Santos MJ, Canas-Silva J, Polido-Pereira J, Pereira Silva JA, Costa JA, Araújo D, Silva C, Santos H, Duarte C, da Silva JA, Pimentel-Santos FM, Branco JC, Karlson EW, Fonseca JE, Solomon DH. (2012) Comparative effectiveness and predictors of response to tumor necrosis factor inhibitor therapies in rheumatoid arthritis. Rheumatology (Oxford) 51:2020-6 

Cascão R, Vidal B, Raquel H, Neves-Costa A, Figueiredo N, Gupta V, Fonseca JE, Moita LF. (2012) Effective treatment of rat adjuvant-induced arthritis by celastrol. Autoimmun Rev. 11:856-62 

Navalho M, Resende C, Rodrigues AM, Ramos F, Gaspar A, Silva JA, Fonseca JE, Campos J, Canhão H.(2012) Bilateral MR Imaging of the Hand and Wrist in Early and Very-Early Inflammatory Arthritis: Tenosynovitis Is Associated with Progression to Rheumatoid Arthritis. Radiology. 264:823-33 

Polido-Pereira J, Rodrigues AM, Canhão H, Saraiva F, da Silva JA, Fonseca JE. (2012) Primary biliary cirrhosis in a rheumatoid arthritis patient treated with rituximab, a case-based review. Clin Rheumatol. 31:385-9 (

Cascão R, Polido-Pereira J, Canhão H, Rodrigues AM, Navalho M, Raquel H, Mourão AF, Resende C , Fonseca JE, Moita LF (2012) Caspase-1 is active since the early phase of Rheumatoid Arthritis. Clin Exp Rheumatol. 30:144 

Pimentel-Santos FM, Ligeiro D, Matos M, Mourão AF, de Sousa EV, Pinto P, Ribeiro A, Santos H, Barcelos A, Godinho F, Cruz M, Fonseca JE, Guedes-Pinto H, Trindade H, Brown MA, Branco JC (2012) ANKH and Susceptibility to and Severity of Ankylosing Spondylitis. J Rheumatol. 39:131-4 . 

Santos MJ, Carmona-Fernandes D, Canhão H, Canas da Silva J, Fonseca JE, Gil V. (2012) Early Vascular Alterations in SLE and RA Patients-A Step towards Understanding the Associated Cardiovascular Risk. PLoS One. 7:e44668 .

Alonso-Perez E, Suarez-Gestal M, Calaza M, Ordi-Ros J, Balada E, Bijl M, Papasteriades C, Carreira P, Skopouli FN, Witte T, Endreffy E, Marchini M, Migliaresi S, Sebastiani GD, Santos MJ, Suarez A, Blanco FJ, Barizzone N, Ruzickova S, Lauwerys BR, Gomez-Reino JJ, Gonzalez A. (2012) Further evidence of subphenotype association with Systemic Lupus Erythematosus susceptibility loci: a case-only study. Plos One 7: e45356. 

Alonso-Perez E, Suarez-Gestal M, Calaza M, Sebastiani GD, Pullmann R, Papasteriades C, Kovacs A, Skopouli FN, Bijl M, Suarez A, Marchini M, Migliaresi S, Carreira P, Ordi-Ros J, Witte T, Ruzickova S, Santos MJ, Barizzone N, Blanco FJ, Lauwerys BR, Gomez-Reino JJ, Gonzalez A, European Consortium of SLE DNA Collections. (2012) Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study. Arthritis Res Ther. Apr 27, 14(2):R94.

Moura RA, Graca L, Fonseca JE. (2012) To B or Not to B the Conductor of Rheumatoid Arthritis Orchestra. Clin Rev Allergy Immunol. 43:281-91 

Madruga Dias J, Costa MM, Romeu JC, Soares-Almeida L, Filipe P, Pereira da Silva JA. (2012) Pachydermodactyly in a 16-year-old adolescent boy. J Clin Rheumatol. 18:246-8. 

Madruga Dias J, Costa MM, Pereira da Silva JA, Viana de Queiroz M. (2012) Parry-Romberg syndrome in an 11-year-old female with neurological manifestations without brain imaging abnormalities. Joint Bone Spine 79:419-21. 

Pimentel-Santos FM, Mourão AF, Ribeiro C, Costa J, Santos H, Barcelos A, Pinto P, Godinho F, Cruz M, Vieira-Sousa E, Santos RA, Rabiais S, Félix J, Fonseca JE, Guedes-Pinto H, Brown MA, Branco JC, CORPOREA Study Group (2012) Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts. Clin Rheumatol 31:447-54. 

Rodrigues AM, Caetano-Lopes J, Vale AC, Vidal B, Lopes A, Aleixo I, Polido-Pereira J, Sepriano A, Perpétuo IP, Monteiro J, Vaz MF, Fonseca JE, Canhão H. (2012) Low osteocalcin/collagen type I bone gene expression ratio is associated with hip fragility fractures. Bone 51:981-9 

Rodrigues AM, Caetano-Lopes J, Vale AC, Aleixo I, Pena AS, Faustino A, Sepriano A, Polido-Pereira J, Vieira-Sousa E, Lucas R, Romeu JC, Monteiro J, Vaz MF, Fonseca JE, Canhão H. (2012) Smoking is a predictor of worse trabecular mechanical performance in hip fragility fracture patients. J Bone Miner Metab 30:692-9.

Santos MJ, Canhão H, Conde M, Fonseca JE, Mourão AF, Ramos F, Costa L, Ramos MP, Cabral M, Estanqueiro P, Melo-Gomes S, Salgado M, Melo-Gomes J. (2012) Portuguese recommendations for the use of biological therapies in children and adolescents with juvenile idiopathic arthritis - December 2011 update. Acta Reumatol Port. 37:48-68. 

Machado P, Bernardo A, Rodrigues A, Malcata A, Nour D, Vieira-Sousa E, Godinho F, Pimentel F, Canhão H, Santos H, Cunha I, Fonseca JE, Costa J, Costa L, Cunha-Miranda L, Maurício L, Cruz M, Santos MJ, Bernardes M, Bogas M, Valente P, Ramiro S, Barcelos A. (2012) Portuguese recommendations for the use of biological therapies in patients with axial spondyloarthritis - December 2011 update. Acta Reumatol Port. 37:40-7. 

Machado P, Bogas M, Ribeiro A, Costa J, Neto A, Sepriano A, Raposo A, Cravo AR, Vilar A, Furtado C, Ambrósio C, Miguel C, Vaz C, Catita C, Nour D, Araújo D, Vieira-Sousa E, Teixeira F, Brandão F, Canhão H, Cordeiro I, Gonçalves I, Ferreira J, Fonseca JE, Silva JA, Romeu J, Ferreira J, Costa L, Maurício L, Cunha-Miranda L, Parente M, Coutinho M, Cruz M, Oliveira M, Salvador MJ, Santos MJ, Pinto P, Valente P, Abreu P, Roque R, Ramiro S, Capela S, Las V, Barcelos A. (2012) 2011 Portuguese recommendations for the use of biological therapies in patients with psoriatic arthritis. Acta Reumatol Port. 37:26-39. 

Laires PA, Canhão H, Araújo D, Fonseca JE, Machado P, Mourão AF, Ramiro S, Romeu JC, Santos MJ, Silva I, Silva JA, Sousa E, Tavares V, Gouveia N, Branco JC.(2012) CoReumaPt Protocol: The Portuguese Cohort of Rheumatic Diseases. Acta Reumatol Port. 37:18-24. 

Machado P, Santos MJ, Fonseca JE. Recommendations of the Portuguese Society of Rheumatology: a contribution towards improving the quality of health care. Acta Reumatol Port. 37:7-8. 

Silva I, Mourão AF, Ramiro S, Rodrigues A, Miguel C, Sampaio L, Faustino A, Vaz C, Canhão H, Cruz M, Neto A, Cravo AR, Ribeiro A, Brandão A, Peixoto D, Medeiros D, Santos FA, Teixeira F, Gonçalves I, Silva JP, Gomes JM, Maurício L, Simões E, Salvador MJ, Silva M, Nero P, Roque R, Barros R, André R, Falcão S, Serra S, Tavares V, Branco JC. (2012) Recomendações portuguesas para o tratamento e controlo farmacológico da dor nas artropatias inflamatórias. Acta Reumatol Port. 37:160-174. 

Roque R, Vinagre F, Gonçalves P, Santos MJ, Canas da Silva J (2012) Manifestações reumáticas da Sífilis Secundária. Acta Reumatol Port. 37:175-9. 

Vidal B, Pinto A, Galvão MJ, Santos AR, Rodrigues A, Cascão R, Abdulghani S, Caetano-Lopes J, Ferreira A, Fonseca JE, Canhao H. Bone histomorphometry revisited. Acta Reumatol Port. 37:294-300. 

Duarte R, Campainha S, Cotter J, Rosa B, Varela P, Correia A, Canhão H, Fonseca JE.  Position paper on tuberculosis screening in patients with immune mediated inflammatory diseases 253 candidates for biological therapy. Acta Reumatol Port. 37:253-259. 

 

2013

Madruga Dias J, Costa MM, Dias S, Almeida A. (2013) Osteomesopyknosis: An incidental discovery due to back pain. Joint Bone Spine 80: 223-4. 

Costa N, Pires AE, Gabriel AM, Goulart LF, Pereira C, Leal B, Queiros AC, Chaara W, Moraes-Fontes MF, Vasconcelos C, Ferreira C, Martins J, Bastos M, Santos MJ, Pereira MA, Martins B, Lima M, João C, Six A, Demengeot J, Fesel C. (2013) Broadened T-cell repertoire diversity in ivIg-treated SLE patients is also related to the individual status of regulatory T-cells. J Clin Immunol 33. 349-60 

Laires PA, Exposto F, Mesquita R, Martins AP, Cunha-Miranda L, Fonseca JE.(2013) Patients' access to biologics in rheumatoid arthritis: a comparison between Portugal and other European countries. Eur J Health Econ 14: 875-85. 

Carmona-Fernandes D, Santos MJ, Canhão H, Fonseca JE.(2013) Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile. BMC Med. 4,11:98. ( 

Cui J Stahl EA Saevarsdottir S Miceli C Diogo D Trynka G Raj T Mirkov MU Canhao H Ikari K Terao C Okada Y Wedrén S Askling J Yamanaka H Momohara S Taniguchi A Ohmura K Matsuda F Mimori T Gupta N Kuchroo M Morgan AW Isaacs JD Wilson AG Hyrich KL Herenius M Doorenspleet ME Tak PP Crusius JB van der Horst-Bruinsma IE Wolbink GJ van Riel PL van de Laar M Guchelaar HJ Shadick NA Allaart CF Huizinga TW Toes RE Kimberly RP Bridges SL Jr Criswell LA Moreland LW Fonseca JE de Vries N Stranger BE De Jager PL Raychaudhuri S Weinblatt ME Gregersen PK Mariette X Barton A Padyukov L Coenen MJ Karlson EW Plenge RM. (2013) Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis. PLoS Genet. 9(3):e1003394. 

Romão VC, Canhão H, Fonseca JE. (2013) Old drugs old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs? BMC Med. 11:17. 

Vale A, Pereira M, Maurício A, Vidal B, Rodrigues A, Caetano-Lopes J, Nazarian A, Fonseca J, Canhão H, Vaz M.(2013) Micro-computed tomography assessment of human femoral trabecular bone for two disease groups (fragility fracture and coxarthrosis): age and gender related effects on the microstructure. Journal of Biomedical Science and Engineering 6:175-184. 

Costa N, Pires AE, Gabriel AM, Goulart LF, Pereira C, Leal B, Queiros AC, Chaara W, Moraes-Fontes MF, Vasconcelos C, Ferreira C, Martins J, Bastos M, Santos MJ, Pereira MA, Martins B, Lima M, João C, Six A, Demengeot J, Fesel C. (2013) Broadened T-cell repertoire diversity in IvIg-treated SLE patients is also related to the individual status of regulatory T-cells. J Clin Immunol. 33:349-60. 

Moura RA, Canhão H, Polido-Pereira J, Rodrigues AM, Navalho M, Mourão AF, Resende C, Campanilho-Marques R, Dias JM, da Silva JA, Graca L, Fonseca JE. (2013) BAFF and TACI Gene Expression Are Increased in Patients with Untreated Very Early Rheumatoid Arthritis. J Rheumatol. 40: 1293-302 

Navalho M, Resende C, Rodrigues AM, Pereira da Silva JA, Fonseca JE, Campos J, Canhão H. (2013) Bilateral evaluation of the hand and wrist in untreated early inflammatory arthritis: a comparative study of ultrasonography and magnetic resonance imaging. J Rheumatol 40: 1282-92. 

Plenge RM, Greenberg JD, Mangravite LM, Derry JM, Stahl EA, Coenen MJ, Barton A, Padyukov L, Klareskog L, Gregersen PK, Mariette X,Moreland LW, Bridges SL Jr, de Vries N, Huizinga TW, Guchelaar HJ; International Rheumatoid Arthritis Consortium (INTERACT), Friend SH,Stolovitzky G. Collaborators: Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Mirkov, Canhao H, Ikari K, Terao C, Okada Y, Wedrï S, Askling J, Yamanaka H,Momohara S, Taniguchi A, Ohmura K, Matsuda F, Mimori T, Gupta N, Kuchroo M, Morgan AW, Isaacs JD, Wilson AG, Hyrich KL,Herenius M, Doorenspleet ME, Tak PP, Crusius JB, van der Horst-Bruinsma IE, Wolbink GJ, van Riel PL, van de Laar M, Guchelaar HJ,Shadick NA, Allaart CF, Huizinga TW, Toes RE, Kimberly RP, Bridges S Jr, Criswell LA, Moreland LW, Fonseca E, de Vries N,Raychaudhuri S, Weinblatt ME, Gregersen PK, Mariette X, Barton A, Alfredsson L, Klareskog L, Padyukov L, Coenen MJ, Karlson EW,Kremer J, Greenberg JD, Plenge RM. (2013) Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge. Nat Genet 45:468-9. 

Vale AC, Faustino J, Reis L, Lopes A, Vidal B, Monteiro J, Fonseca JE, Canhao H, Vaz MF. (2013) Effects of the Shear Strain Rate on the Torsion of Human Trabecular Bone. J Biomech Eng. 135: 121005 

Lin C, Karlson EW, Canhao H, Miller TA, Dligach D, Chen PJ, Perez RN, Shen Y, Weinblatt ME, Shadick NA, Plenge RM, Savova GK. (2013) Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records. PLoS One. 8(8):e69932. 

Vale AC, Aleixo IP, Lúcio M, Saraiva A, Caetano-Lopes J, Rodrigues A, Amaral PM, Rosa LG, Monteiro J, Fonseca JE, Vaz MF, Canhão H. (2013) At the moment of occurrence of a fragility hip fracture, men have higher mechanical properties values in comparison with women.BMC Musculoskelet Disord 14:295. 

Cáliz R, Canet LM, Lupiañez CB, Canhão H, Escudero A, Filipescu I, Segura-Catena J, Soto-Pino MJ, Expósito-Ruiz M, Ferrer MÁ, García A, Romani L, González-Utrilla A, Vallejo T, Pérez-Pampin E, Hemminki K, Försti A, Collantes E, Fonseca JE, Sainz J. (2013) Gender-Specific Effects of Genetic Variants within Th1 and Th17 Cell-Mediated Immune Response Genes on the Risk of Developing Rheumatoid Arthritis. PLoS One. 8(8):e72732. 

Laires PA, Mesquita R, Veloso L, Martins AP, Cernadas R, Fonseca JE. (2013) Patient's access to healthcare and treatment in rheumatoid arthritis: the views of stakeholders in Portugal. BMC Musculoskelet Disord 14:279. 

Bettencourt BF, Rocha FL, Alves H, Amorim R, Caetano-Lopes J, Vieira-Sousa E, Pimentel-Santos F, Lima M, Porto G, Branco JC, Fonseca JE, Bruges-Armas J. (2013) Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals. Rheumatology (Oxford). 52: 2168-76. 

Gonçalves MJ, Rodrigues AM, Canhão H, Fonseca JE.(2013) Osteoporosis: From Bone Biology to Individual Treatment Decision. Acta Med Port. 26:445-455. 

Fonseca JE. (2013) Biobanco-IMM, Lisbon Academic Medical Centre: A Case Study. Acta Med Port. 26:312-4.  

Reis C, Mestre C, Canhão H. (2013) Prevalence of fatigue in a group of airline pilots. Aviat Space Environ Med. 84:828-33. 

Marques A, Mota A, Canhão H, Romeu JC, Machado P, Ruano A, Barbosa AP, Dias AA, Silva D, Araújo D, Simões E, Aguas F, Rosendo I, Silva I, Crespo J, Alves JD, Costa L, Mascarenhas M, Lourenço O, Ferreira PL, Lucas R, Roque R, Branco JC, Tavares V, Johansson H, Kanis J, Pereira da Silva JA. A FRAX model for the estimation of osteoporotic fracture probability in Portugal. Acta Reumatol Port. 38:104-112 

Santos MJ (2013) Systemic rheumatic diseases: beyond classification criteria. Acta Reumatol Port. 38:7-8. 

C. Ponte, E. Vieira-Sousa, F. Saraiva, R. Sousa, A. Francisco, S. Livraghi, J.C. Romeu, J.A. Pereira da Silva.(2013) Acute Low Back Pain - A Clinical and Imaging Challenge. Acta Reumatol Port. 2:133-135. 

 

2014

Madruga Dias JA, Rosa RS, Perpétuo I, Rodrigues AM, Janeiro A, Costa MM, Gaião L, Pereira da Silva JA, Fonseca JE, Miltenberger-Miltenyi G.(2014) Pachydermoperiostosis in an African patient caused by a Chinese/Japanese SLCO2A1 mutation-Case report and review of literature. Semin Arthritis Rheum 43: 566-9.

Caetano-Lopes J, Rodrigues A, Lopes A, Vale AC, Pitts-Kiefer MA, Vidal B, Perpétuo IP, Monteiro J, Konttinen YT, Vaz MF, Nazarian A, Canhão H, Fonseca JE.(2014) Rheumatoid Arthritis Bone Fragility Is Associated With Upregulation of IL17 and DKK1 Gene Expression. Clin Rev Allergy Immunol. 47: 38-45. 

Gonçalves MJ, Romão VC. Images in clinical medicine. (2014) Saber tibia in Paget's disease of bone. N Engl J Med. 371:2417. 

Cascão R, Vidal B, Raquel H, Neves-Costa A, Figueiredo N, Gupta V, Fonseca JE, Moita LF. (2014) Potent anti-inflammatory and antiproliferative effects of gambogic acid in a rat model of antigen-induced arthritis. Mediators Inflamm. 2014:195327. 

Alonso-Perez E, Suarez-Gestal M, Calaza M, Blanco FJ, Suarez A, Santos MJ, Papasteriades C, Carreira P, Pullmann R, Ordi-Ros J, Marchini M, Skopouli FN, Bijl M, Barrizone N, Sebastiani GD, Migliaresi S, Witte T, Lauwerys BR, Kovacs A, Ruzickova S, Gomez-Reino JJ, Gonzalez A; European Consortium of SLE DNA Collections. (2014) Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus. Arthritis Res Ther 16 (3):R128. 

Freira S, Fonseca H, Ferreira PD, Vasconcelos P, Fonseca JE. (2014) SAPHO Syndrome in an Adolescent: A Clinical Case With Unusual Severe Systemic Impact. J Adolesc Health 55:304-6. 

Sanches BF, Martins T, Santos MJ, Azeredo P. Acute acalculous cholecystitis in a patient with juvenile dermatomyositis. (2014) BMJ Case Rep. 19; pii: bcr2014205066 

Romão VC, Lima A, Bernardes M, Canhão H, Fonseca JE. (2014) Three decades of low-dose methotrexate in rheumatoid arthritis: Can we predict toxicity? Imunol Res 60:289-310 

Mourão AF, Santos MJ, Melo-Gomes J, Martins FM, Costa JA, Ramos F, Brito I, Duarte C, Figueira R, Figueiredo G, Furtado C, Lopes A, Oliveira M, Rodrigues A, Salgado M, Sousa M, Branco JC, Fonseca JE, Canhão H. (2014) Using the juvenile arthritis disease activity score based on erythrocyte sedimentation rate or C-reactive protein level: results from the portuguese register. Arthritis Care Res (Hoboken) 66:585-91. 

Cambridge G, Moura RA, Santos T, Khawaja AA, Polido-Pereira J, Canhão H, Leandro MJ, Fonseca JE. (2014) Expression of the inherently autoreactive idiotope 9G4 on autoantibodies to citrullinated peptides and on rheumatoid factors in patients with early and established rheumatoid arthritis. PLoS One 9(9):e107513. 

Lucas R, Ramos E, Prata M, Rodrigues AM, Costa L, Severo M, Canhão H, Fonseca JE, Barros H. (2014) Changes in serum RANKL and OPG with sexual development and their associations with bone turnover and bone mineral density in a cohort of girls. Clin Biochem 47:1040-6. 

Okada Y, Diogo D, Greenberg JD, Mouassess F, Achkar WA, Fulton RS, Denny JC, Gupta N, Mirel D, Gabriel S, Li G, Kremer JM, Pappas DA, Carroll RJ, Eyler AE, Trynka G, Stahl EA, Cui J, Saxena R, Coenen MJ, Guchelaar HJ, Huizinga TW, Dieudé P, Mariette X, Barton A, Canhão H, Fonseca JE, de Vries N, Tak PP, Moreland LW, Bridges SL Jr, Miceli-Richard C, Choi HK, Kamatani Y, Galan P, Lathrop M, Raj T, De Jager PL, Raychaudhuri S, Worthington J, Padyukov L, Klareskog L, Siminovitch KA, Gregersen PK, Mardis ER, Arayssi T, Kazkaz LA, Plenge RM. (2014) Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene. PLoS One 9(2):e87645. 

Campanilho-Marques R, Ramos F, Canhão H, Fonseca JE. (2014) Remission induced by infliximab in a childhood polyarteritis nodosa refractory to conventional immunosuppression and rituximab. Joint Bone Spine 81:277-8. 

Kearsley-Fleet L, Závada J, Hetland ML, Nordström DC, Aaltonen KJ, Listing J, Zink A, Gati T, Rojkovich B, Iannone F, Gremese E, van Riel PL, van de Laar MA, Lie E, Kvien TK, Canhão H, Fonseca JE, Rotar Z, Loza E, Carmona L, Askling J, Johansson K, Finckh A, Dixon WG, Hyrich KL; on behalf of the EULAR Study Group for Registers and Observational Drug Studies. (2014) The EULAR Study Group for Registers and Observational Drug Studies: comparability of the patient case mix in the European biologic disease modifying anti-rheumatic drug registers. Rheumatology (Oxford) 54: 1074-9.

Campanilho-Marques R, Bogas M, Ramos F, Santos MJ, Fonseca JE. (2014) Prognostic value of antinuclear antibodies in juvenile idiopathic arthritis and anterior uveitis. Results from a systematic literature review. Acta Reumatol Port 39:116-22. 

Araújo F, Cordeiro I, Teixeira F, Rovisco J, Ramiro S, Mourão AF, Costa JA, Pimentão JB, Malcata A, Santos MJ, Branco JC. (2014) Portuguese Recommendations for the Diagnosis and Management of Gout. Acta Reumatol Port 39:158-71 

Araújo F, Cordeiro I, Teixeira F, Gonçalves J, Fonseca JE.(2014) Pharmacology of biosimilar candidate drugs in rheumatology: a literature review. Acta Reumatol Port. 39:19-26. 

Dias JM, Costa MM, Canhão H, Saraiva F, Silva JA. (2014) Musculoskeletal ultrasound in Paediatric Rheumatology: a retrospective analysis. Acta Reumatol Port 39: 309-14. 

Fonseca JE, Gonçalves J, Araújo F, Cordeiro I, Teixeira F, Canhão H, da Silva JA, Garcês S, Miranda LC, Ramiro S, Roxo A, Pimentel-Santos FM, Tavares V, Neto A, Sepriano A, Malcata A, Faustino A, Silva C, Ambrósio C, Duarte C, Miguel C, Barcelos F, Santos H, Cunha I, Ramos JC, Gomes JA, Pimentão JB, CostaL, Maurício L, Silva M, Bernardes M, Bogas M, Coelho PC, Monteiro P, Aguiar R, André R, Leitão R, Pimenta S, Meirinhos T, Fernandes S, Las V, Castelão W; Sociedade Portuguesa de Reumatologia. (2014) The Portuguese Society of Rheumatology position paper on the use of biosimilars. Acta Reumatol Port 39:60-71. 

Fonseca JE.(2014) Revisiting rheumatic diseases and cancer.Acta Reumatol Port 39:9-10. 

Ferraria N, Marques JG, Ramos F, Lopes G, Fonseca JE, Neves MC.(2014) Chronic recurrent multifocal osteomyelitis: case series of four patients treated with biphosphonates. Acta Reumatol Port 39:38-45.

Campanilho-Marques R, Ramos F, Canhão H, Fonseca JE. Remission induced by infliximab in a childhood polyarteritis nodosa refractory to conventional immunosuppression and rituximab. Joint, bone, spine : revue du rhumatisme. 2014; 81(3):277-8.

Campanilho-Marques R, Novelli V, Brogan PA, Eleftheriou D. Polyarticular septic arthritis in an 11-year-old child. Clinical rheumatology. 2014; 33(8):1181-2.

Campanilho-Marques R, Brogan PA. Mevalonate kinase deficiency in two sisters with therapeutic response to anakinra: case report and review of the literature. Clinical rheumatology. 2014; 33(11):1681-4.

Ponte C, Macieira C. (2014) Beyond an inflamed ear. Acta Med Port  27:790. 

 

2015

Martins FM, da Silva JA, Santos MJ, Vieira-Sousa E, Duarte C, Santos H, Costa JA, Pimentel-Santos FM, Cunha I, Cunha Miranda L, Nóvoa T, Cruz M, Bernardes M, Araujo D, Pereira Silva JA, Silva JC, Branco JC, Gomes JA, Faustino A, Fonseca JE, Canhão H. (2015) DAS28, CDAI and SDAI cut-offs do not translate thesame information: results from the Rheumatic Diseases Portuguese Register Reuma.pt. Rheumatology (Oxford) 54: 286-91.

Gonçalves MJ, Sousa S, Inês LS, Duarte C, Borges J, Silva C, Romão VC, Terroso G, Bernardes M, Cerqueira M, Raposo A, Sequeira G, Barcelos A, Macieira C, Canas da Silva J, Costa L, Pereira da Silva JA, Cunha-Miranda L, Da Silva JA, Canhão H, Santos MJ. (2015) Characterization of damage in Portuguese lupus patients: analysis of a national lupus registry. Lupus 24: 256-62.

Araujo GR, Fonseca JE, Fujimura PT, Cunha-Junior JP, Silva CH, Mourão AF, Canhão H, Goulart LR, Gonçalves J, Ueira-Vieira C. (2015) Anti-type II collagen antibodies detection and avidity in patients with oligoarticular and polyarticular forms of juvenile idiopathic arthritis. Immunol Lett 165 :20-5 

Canhão H, Rodrigues AM, Santos MJ, Carmona-Fernandes D, Bettencourt BF, Cui J, Rocha FL, Canas Silva J, Polido-Pereira J, Pereira Silva JA, Costa JA, Araujo D, Silva C, Santos H, Duarte C, Cáliz R, Filipescu I, Pimentel-Santos F, Branco J, Sainz J, Plenge RM, Solomon DH, Bruges-Armas J, Da Silva JA, Fonseca JE, Karlson EW. (2015) TRAF1/C5 but Not PTPRC Variants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy. Biomed Res Int. 2015:490295 

Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, Kiemeney LA, Mariette X, Richard-Miceli C, Canhão H, Fonseca JE, de Vries N, Tak PP, Crusius JB, Nurmohamed MT, Kurreeman F, Mikuls TR, Okada Y, Stahl EA, Larson DE, Deluca TL, O'Laughlin M, Fronick CC, Fulton LL, Kosoy R, Ransom M, Bhangale TR, Ortmann W, Cagan A, Gainer V, Karlson EW, Kohane I, Murphy SN, Martin J, Zhernakova A, Klareskog L, Padyukov L, Worthington J, Mardis ER, Seldin MF, Gregersen PK, Behrens T, Raychaudhuri S, Denny JC, Plenge RM. (2015) TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits. PLoS One 10(4):e0122271. 

Canet LM, Filipescu I, Cáliz R, Lupiañez CB, Canhão H, Escudero A, Segura-Catena J, Soto-Pino MJ, Ferrer MA, García A, Romani L, Pérez-Pampin E, González-Utrilla A, López Nevot MA, Collantes E, Fonseca JE, Sainz J. (2015) Genetic variants within the TNFRSF1B gene and susceptibility to rheumatoid arthritis and response to anti-TNF drugs: a multicenter study. Pharmacogenet Genomic 25 :323-33 

Yeremenko N, Zwerina K, Rigter G, Pots D, Fonseca J, Zwerina J, Schett G, Baeten D. (2015) TNF-α and IL-6 differentially regulate Dkk-1 in the inflamed arthritic joint. Arthritis Rheumatol 67:2071-5 

Smolen JS, Breedveld FC, Burmester GR, Bykerk V, Dougados M, Emery P, Kvien TK, Navarro-Compán MV, Oliver S, Schoels M, Scholte-Voshaar M, Stamm T, Stoffer M, Takeuchi T, Aletaha D, Andreu JL, Aringer M, Bergman M, Betteridge N, Bijlsma H, Burkhardt H, Cardiel M, Combe B, Durez P, Fonseca JE, Gibofsky A, Gomez-Reino JJ, Graninger W, Hannonen P, Haraoui B, Kouloumas M, Landewe R, Martin-Mola E, Nash P, Ostergaard M, Östör A, Richards P, Sokka-Isler T, Thorne C, Tzioufas AG, van Vollenhoven R, de Wit M, van der Heijde D. (2015) Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis 75:3-15.

Almeida B, Campanilho-Marques R, Arnold K, Pilkington CA, Wedderburn LR, Nistala K. Analysis of Published Criteria for Clinically Inactive Disease in a Large Juvenile Dermatomyositis Cohort Shows That Skin Disease Is Underestimated. Arthritis & rheumatology (Hoboken, N.J.). 2015; 67(9):2495-502.

Romão VC, Santos MJ, Polido-Pereira J, Duarte C, Nero P, Miguel C, Costa JA, Bernardes M, Pimentel-Santos FM, Barcelos F, Costa L, Melo Gomes JA, Pereira da Silva JA, Branco JC, Canas da Silva J, Pereira da Silva JA, Fonseca JE, Canhão H. (2015) Comparative Effectiveness of Tocilizumab and TNF Inhibitors in Rheumatoid Arthritis Patients: Data from the Rheumatic Diseases Portuguese Register, Reuma.pt. Biomed Res Int 2015:279890.

Araujo GR, Vaz ER, Fujimura PT, Fonseca JE, de Lima LM, Canhão H, Venturini G, Cardozo KH, Carvalho VM, Napimoga MH, Goulart LR, Gonçalves J, Ueira-Vieira C. (2015) Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of Carbonic Anhydrase III selected in a murine model by phage display. Arthritis Res Ther 17:168. 

Vieira-Sousa E, van Duivenvoorde LM, Fonseca JE, Lories RJ, Baeten DL. (2015) Animal models as a tool to dissect pivotal pathways driving spondyloarthritis. Arthritis Rheumatol 67:2813-27.

Rodrigues AM, Gouveia N, Costa LP, Eusébio M, Ramiro S, Machado P, Mourão AF, Silva I, Laires P, Sepriano A, Araújo F, Coelho PS, Gonçalves S, Zhao A, Fonseca JE, Almeida JM, Tavares V, da Silva JA, Barros H, Cerol J, Mendes J, Carmona L, Canhão H, Branco JC. EpiReumaPt- the study of Rheumatic and Musculoskeletal diseases in Portugal: A detailed view of the methodology. Acta Reumatol Port 40:110-124. 

Mourão AF, Santos MJ, Mendonça S, Oliveira-Ramos F, Salgado M, Estanqueiro P, Melo-Gomes J, Martins F, Lopes A, Bettencourt BF, Bruges-Armas J, Costa J, Furtado C, Figueira R, Brito I, Branco J, Fonseca JE, Canhão H. (2015) Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiopathic Arthritis: Data from Reuma.pt. J Immunol Res 2015:706515 

Laires PA, Dezerto R, Mesquita R, Fonseca JE, Cernadas R, Miranda LC, Silva JC, Costa L, Nogueira AM. (2015) Effectiveness of A Referral Program for Early Arthritis Diagnosis At Primary Care Centers in Portugal - Preliminary Results from the Siara Study. Value Health 18:A658.

Vieira-Sousa E, Machado PM, Costa J, Ribeiro A, Aguiar R, Cerqueira M, Neto A, Bernardo A, Cordeiro A, Duarte C, Vinagre F, Canhão H, Santos H, Neves JS, Cunha-Miranda L, Silva M, Santos MJ, Bernardes M, Bogas M, Abreu P, Viana-Queiroz M, Barros R, Falcão S, Pimenta S, Teixeira V, Fonseca JE, Barcelos A. (2015) Portuguese recommendations for the use of biological therapies in patients with psoriatic arthritis - 2015 update. Acta Reumatol Port 40:275-290. 

Cascão R, Vidal B, Lopes IP, Paisana E, Rino J, Moita LF, Fonseca JE. (2015) Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats. PLoS One 10(12):e0142448 

Perpétuo IP, Raposeiro R, Caetano-Lopes J, Vieira-Sousa E, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE. (2015) Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Ankylosing Spondylitis. PLoS One 10(12):e0144655. 

Vidal B, Cascão R, Vale AC, Cavaleiro I, Vaz MF, Brito JA, Canhão H, Fonseca JE. Arthritis induces early bone high turnover, structural degradation and mechanical weakness. PLoS One 10(1):e0117100 

Traunecker E, Gardner R, Fonseca JE, Polido-Pereira J, Seitz M, Villiger PM, Iezzi G, Padovan E. Blocking of LFA-1 enhances expansion of Th17 cells induced by human CD14(+) CD16(++) nonclassical monocytes. Eur J Immunol. 45:1414-25.

Kearsley-Fleet L, Závada J, Hetland ML, Nordström DC, Aaltonen KJ, Listing J, Zink A, Gati T, Rojkovich B, Iannone F, Gremese E, van Riel PL, van de Laar MA, Lie E, Kvien TK, Canhão H, Fonseca JE, Rotar Ž, Loza E, Carmona L, Askling J, Johansson K, Finckh A, Dixon WG, Hyrich KL; EULAR Study Group for Registers and Observational Drug Studies. (2015) The EULAR Study Group for Registers and Observational Drug Studies: comparability of the patient case mix in the European biologic disease modifying anti-rheumatic drug registers. Rheumatology (Oxford). 54:1074-9 

Martins FM, da Silva JA, Santos MJ, Vieira-Sousa E, Duarte C, Santos H, Costa JA, Pimentel-Santos FM, Cunha I, Cunha Miranda L, Nóvoa T, Cruz M, Bernardes M, Araujo D, Pereira Silva JA, Silva JC, Branco JC, Gomes JA, Faustino A, Fonseca JE, Canhão H. (2015) DAS28, CDAI and SDAI cut-offs do not translate the same information: results from the Rheumatic Diseases Portuguese Register Reuma.pt. Rheumatology (Oxford) 54:286-91.

Pires J, Gonçalves MJ, Costa A, Pereira A, Gonçalves A, Romeu JC. (2015) Polyarteritis nodosa: the angiography usefulness. Acta Reumatol Port 40:193-4. 

Gonçalves MJ, Sousa S, Inês LS, Cunha-Miranda L, Canhão H, Santos MJ. (2015) The weaker sex: Characterization of gender disparities in a nationwide lupus register (Reuma.pt/SLE). Joint Bone Spine 82:378-80. 

Gouveia N, Rodrigues AM, Ramiro S, Machado P, da Costa LP, Mourão AF, Silva I, Rego T, Laires P, André R, Mauricio L, Romeu JC, Tavares V, Cerol J, Canhão H, Branco JC. (2015) How to perform a national population based study – a practical guide. Acta Reumatol Port 40:128-136. 

Inês L, Silva C, Galindo M, López-Longo FJ, Terroso G, Romão VC, Rúa-Figueroa I, Santos MJ, Pego-Reigosa JM, Nero P, Cerqueira M, Duarte C, Miranda LC, Bernardes M, Gonçalves MJ, Mouriño-Rodriguez C, Araújo F, Raposo A, Barcelos A, Couto M, Abreu P, Otón-Sanchez T, Macieira C, Ramos F, Branco JC, Silva JA, Canhão H, Calvo-Alén J; for the Rheumatic Diseases Registry of the Portuguese Society of Rheumatology (Reuma.pt) and for the Registry of SLE Patients of the Spanish Society of Rheumatology (RELESSER). (2015) Classification of Systemic lupus erythematosus: Systemic Lupus International   Collaborating Clinics versus American College of Rheumatology criteria. Arthritis Care Res (Hoboken) 67: 1180-5.

Loureiro M, Sousa S, Santos MJ. (2015) Esclerose sistémica juvenil. Acta Med Port 28:785-78. 

Romão VC, Pitzalis C. (2015) Synovial heterogeneity in rheumatoid arthritis: the key for rational patient stratification? Acta Reumatol Port 40:6-8. 

Finckh A, Neto D, Iannone F, Loza E, Lie E, van Riel P, Hetland ML, Pavelka K, Gottenberg JE, Canhão H, Mariette X, Turesson C. (2015) The impact of patient heterogeneity and socioeconomic factors on abatacept retention in rheumatoid arthritis across nine European countries. RMD Open 1(1):e000040. 

Walker UA, Jaeger VK, Chatzidionysiou K, Hetland ML, Hauge EM, Pavelka K, Nordström DC, Canhão H, Tomšič M, van Vollenhoven R, Gabay C. (2016) Rituximab done: what's next in rheumatoid arthritis? A European observational longitudinal study assessing the effectiveness of biologics after rituximab treatment in rheumatoid arthritis. Rheumatology (Oxford) 55: 230-6.

Canet LM, Cáliz R, Lupiañez CB, Canhão H, Martinez M, Escudero A, Filipescu I, Segura-Catena J, Soto-Pino MJ, Ferrer MA, García A, Romani L, Pérez-Pampin E, González-Utrilla A, López Nevot MÁ, Collantes E, Fonseca JE, Sainz J. (2015) Genetic variants within immune-modulating genes influence the risk of developing rheumatoid arthritis and anti-TNF drug response: a two-stage case-control study. Pharmacogenet Genomics 25:432-43.

Branco JC, Canhão H. (2015) EpiReumaPt - development and consequences. Acta Reumatol Port 40:106-109. 

Oliveira P, Zejnilovic L, Canhão H, von Hippel E. (2015) Innovation by patients with rare diseases and chronic needs. Orphanet J Rare Dis 10:41 

Laires PA, Canhão H, Gouveia M. (2015) Indirect costs associated with early exit from work attributable to rheumatic diseases. Eur J Public Health 25:677-82 

Gonçalves MJ, Sousa S, Inês LS, Duarte C, Borges J, Silva C, Romão VC, Terroso G, Bernardes M, Cerqueira M, Raposo A, Sequeira G, Barcelos A, Macieira C, Canas da Silva J, Costa L, Pereira da Silva JA, Cunha-Miranda L, Da Silva JA, Canhão H, Santos MJ. (2015)   Characterization of damage in Portuguese lupus patients: analysis of a national lupus registry. Lupus. 24:256-62.

Fernandes S, Capela S, Resende C, Romeu JC, Pereira da Silva JA. (2015) Severe vertical atlanto-axial subluxation in rheumatoid arthritis. Acta Reumatol Port 40:91-92.

Fernandes S, Romeu JC, Pereira da Silva JA. (2015) Platelet Rich Plasma: What should the rheumatologist expect? Acta Reumatol Port 40: 214-222.

 

2016

Gabay C, Riek M, Hetland ML, Hauge EM, Pavelka K, Tomšič M, Canhao H, Chatzdionysiou K, Lukina G, Nordström DC, Lie E, Ancuta I, Hernández MV, van Riel PL, van Vollenhoven R, Kvien TK. (2016) Effectiveness of tocilizumab with and without synthetic disease-modifying antirheumatic drugs in rheumatoid arthritis: results from a European collaborative study. Ann Rheum Dis 75: 1336-42 

Mourão AF, Santos MJ, Melo Gomes JA, Martins FM, Mendonça SC, Oliveira Ramos F, Fernandes S, Salgado M, Guedes M, Carvalho S, Costa JA, Brito I, Duarte C, Furtado C, Lopes A, Rodrigues A, Sequeira G, Branco JC, Fonseca JE, Canhão H. (2016) Effectiveness and long-term retention of anti-tumour necrosis factor treatment in juvenile and adult patients with juvenile idiopathic arthritis: data from Reuma.pt. Rheumatology (Oxford) 55:697-703.

Gouveia N, Rodrigues A, Eusébio M, Ramiro S, Machado P, Canhão H, Branco JC. (2016) Prevalence and social burden of active chronic low back pain in the adult Portuguese population: results from a national survey. Rheumatol Int 36: 183-97.

Humby F, Kelly S, Bugatti S, Manzo A, Filer A, Mahto A, Fonseca JE, Lauwerys B, D'Agostino MA, Naredo E, Lories R, Montecucco C, Tak PP, Fitzgerald O, Smith MD, Veale DJ, Choy EH, Strand V, Pitzalis C. (2016) Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter-determining Validation Requirements. J Rheumatol 43: 208-13.

Araujo F, Goncalves J, Fonseca JE. (2016) Biosimilar DMARDs: What Does the Future Hold? Drugs 76: 629-637. 

Araujo GR, Fujimura PT, Vaz ER, Silva TA, Rodovalho VR, Britto-Madurro AG, Madurro JM, Fonseca JE, Silva CHM, Santos PS, Mourao AF, Canhao H, Goulart LR, Goncalves J, Ueira-Vieira C. (2016) A novel reactive epitope-based antigen targeted by serum autoantibodies in oligoarticular and polyarticular juvenile idiopathic arthritis and development of an electrochemical biossensor. Immunobiology 224:634-640. 

Araujo FC, Goncalves J, Fonseca, JE. (2016) Pharmacoeconomics of Biosimilars: What Is There to Gain from Them? Curr Rheumatol Rep. 18: 50. 

Gonçalves J, Araújo F, Cutolo M, Fonseca JE. (2016)  Biosimilar monoclonal antibodies: preclinical and clinical development aspects. Clin Exp Rheumatol 34: 698-705. 

Barreira SC, Fonseca JE. (2016) The Impact of Conventional and Biological Disease Modifying Antirheumatic Drugs on Bone Biology. Rheumatoid Arthritis as a Case Study. Clin Rev Allergy Immunol. 51:100-109. 

Santos MJ, Canhao H, Faustino A, Fonseca JE. (2016) Reuma.pt: A Case Study. Acta Med Port 29:83-84. 

Xerinda S, Oliveira O, Lucas R, Fonseca JE, Varela P, Cotter J, Duarte R. (2016) Gaps and barriers to tuberculosis screening among anti-tumor necrosis factor prescribers.  Acta Reumatol Port 41: 382-4.

Castro AM, Fernandes DC, Rodrigues AM, Pedro LM, Santos MJ, Canhão H, Fonseca JE. (2016) Incidence and predictors of cardiovascular events in a cohort of patients with rheumatoid arthritis. Acta Reumatol Port 41:213-219.

Fernandes S, Vieira-Sousa E, Furtado C, Costa A, Barros R, Fonseca JE. (2016) A diagnosis of disseminated tuberculosis based on knee arthroscopic guided synovial biopsy in the context of monoarthritis. Acta Reumatol Port 4:256-259.

Santos MJ, Conde M, Mourão AF, Ramos FO, Cabral M, Brito I, Ramos MP, Marques RC, Gomes SM, Guedes M, Gonçalves MJ, Estanqueiro P, Zilhão C, Rodrigues M, Henriques C, Salgado M, Canhão H, Fonseca JE, Gomes JM. (2016) 2016 update of the Portuguese recommendations for the use of biological therapies in children and adolescents with Juvenile Idiopathic Arthritis. Acta Reumatol Port 41:194-212.

Oliveira-Ramos F, Eusébio M, M Martins F, Mourão AF, Furtado C, Campanilho-Marques R, Cordeiro I, Ferreira J, Cerqueira M, Figueira R, Brito I, Canhão H, Santos MJ, Melo-Gomes JA, Fonseca JE. (2016) Juvenile idiopathic arthritis in adulthood: fulfilment of classification criteria for adult rheumatic diseases, long-term outcomes and predictors of inactive disease, functional status and damage. RMD Open 2(2):e000304.

Azevedo V, Hassett B, Fonseca JE, Atsumi T, Coindreau J, Jacobs I, Mahgoub E, O'Brien J, Singh E, Vicik S, Fitzpatrick B. (2016) Differentiating biosimilarity and comparability in biotherapeutics. Clin Rheumatol 35: 2877-86.

Fernandes S, Almeida P, Melo-Gomes J, Romeu JC. (2016) Brown Tumors in Secondary Hyperparathyroidism in a Patient With Lupus Nephritis J Clin Rheumatol 22: 438-439.

Marques A, Rodrigues AM, Romeu JC, Ruano A, Barbosa AP, Simões E, Águas F, Canhão H, Alves JD, Lucas R, Branco JC, Laíns J, Mascarenhas M, Simões S, Tavares V, Lourenço O, da Silva JA. (2016)  Multidisciplinary Portuguese recommendations on DXA request and indication to treat in the prevention of fragility fractures. Acta Reumatol Port 2016; 41: 305-321.

Sousa S, Gonçalves MJ, Inês LS, Eugénio G, Jesus D, Fernandes S, Terroso G, Romão VC, Cerqueira M, Raposo A, Couto M, Nero P, Sequeira G, Nóvoa T, Melo Gomes JA, da Silva JC, Costa L, Macieira C, Silva C, Silva JA, Canhão H, Santos MJ. (2016)  Clinical features and long-term outcomes of systemic lupus erythematosus: comparative data of childhood, adult and late-onset disease in a national register. Rheumatol Int 36: 955-60. 

 

Cordeiro I, Duarte AC, Ferreira JF, Gonçalves MJ, Meirinhos T, Rocha TM, Romão VC, Sousa S, Guedes M, Conde M, Abreu C, Aleixo MJ, Santos MJ. (2016) Recommendations for Vaccination in Adult Patients with Systemic Inflammatory Rheumatic Diseases from the Portuguese Society of Rheumatology. Acta Reumatol Port 41: 112-130. 

 

Cortes M, Fernandes S, Teixeira V.  (2016) Upper gastrointestinal bleeding in a patient with Sjögren syndrome. Rev Esp Enferm Dig. 108:576. 

Barreto Cortes M, Teixeira V, Fernandes SR, Rego F. (2016) Haemophilus parainfluenzae endocarditis with systemic embolisation following maxillary sinusitis. BMJ Case Rep. 2016 -216473. 

Smolen JS, Breedveld FC, Burmester GR, Bykerk V, Dougados M, Emery P, Kvien TK, Navarro-Compán MV, Oliver S, Schoels M, Scholte-Voshaar M, Stamm T, Stoffer M, Takeuchi T, Aletaha D, Andreu JL, Aringer M, Bergman M, Betteridge N, Bijlsma H, Burkhardt H, Cardiel M, Combe B, Durez P, Fonseca JE, Gibofsky A, Gomez-Reino JJ, Graninger W, Hannonen P, Haraoui B, Kouloumas M, Landewe R, Martin-Mola E, Nash P, Ostergaard M, Östör A, Richards P, Sokka-Isler T, Thorne C, Tzioufas AG, van Vollenhoven R, de Wit M, van der Heijde D. (2016) Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis 75:3-15. 

Bentow C, Lakos G, Martis P, Wahl E, Garcia M,  Viñas O, Espinosa G, Cervera G, Sjowall G, Carmona-Fernandes D, Santos MJ,  Hanly JG, Mahler M. (2016) International multi-center evaluation of a novel chemiluminescence assay for the detection of anti-dsDNA antibodies. Lupus 25:864-72. 

Almeida S, Braga M, Santos MJ. (2016) Juvenile dermatomyositis with anti-signal recognition particle antibodies: a case report. Acta Reumatol Port 41:162-4. 

Courvoisier DS, Alpizar-Rodriguez D, Gottenberg JE, Hernandez MV, Iannone F, Lie E, Santos MJ, Pavelka K, Turesson C, Mariette X, Choquette D, Hetland ML, Finckh A. (2016) Rheumatoid Arthritis Patients after Initiation of a New Biologic Agent: Trajectories of Disease Activity in a Large Multinational Cohort Study. EBioMedicine. 11:302-306. 

Teixeira L, Fonseca AR, Eugénio G, Rodrigues M, Khmelinskii N, Fernandes S, Serra S, Costa T, Santos MJ. (2016) Management of infections in rheumatic patients receiving biological therapies. The Portuguese Society of Rheumatology recommendations. Acta Reumatol Port 41: 287-304.

Campanilho-Marques R, Almeida B, Deakin C, Arnold K, Gallot N, de Iorio M, Nistala K, Pilkington CA, Wedderburn LR. (2016) Comparison of the utility and validity of three scoring tools to detect skin disease in patients with Juvenile Dermatomyositis. Arthritis Care Res 68: 1514–21. 

Sepriano A, Ramiro S, van der Heijde D, Ávila-Ribeiro P, Fonseca R, Borges J, Teixeira L, Carvalho PD, Cerqueira M, Neves J, Meirinhos T, Barcelos A, Sequeira G, Salvador MJ, Canas da Silva J, Santos H, Bernardes M, Vieira-Sousa E, Canhão H, Branco JC, Pimentel-Santos F, Landewé R. (2016) Effect of Comedication With Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Retention of Tumor Necrosis Factor Inhibitors in Patients With Spondyloarthritis: A Prospective Cohort Study. Arthritis Rheumatol 68:2671-9. 

Tang MW, Reedquist KA, Garcia S, Fernandez BM, Codullo V, Vieira-Sousa E, Goffin V, Reuwer AQ, Twickler MT, Gerlag DM, Tak PP. (2016) The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation. Rheumatology (Oxford). 55: 2248-59. 

Landi M, Maldonado-Ficco H, Perez-Alamino R, Maldonado-Cocco JA, Citera G, Arturi P, Sampaio-Barros PD, Flores Alvarado DE, Burgos-Vargas R, Santos E, Palleiro D, Gutiérrez MA, Vieyra-Sousa E, Pimentel-Santos F, Paira SO, Berman A, Barrezueta CV, Vazquez-Mellado J, Collantes-Estevez E; RESPONDIA Group. Fundación Reumatológica Argentina “Dr. Osvaldo García Morteo. (2016) Gender differences among patients with primary ankylosing spondylitis and spondylitis associated with psoriasis and inflammatory bowel disease in an iberoamerican spondyloarthritis cohort. Medicine (Baltimore) 295(51):e5652. 

Vieira Sousa E, Sepriano A, Pimentel Santos F. (2016) Investigator initiated trials in Portuguese rheumatology. Acta Reumatol Port. 41:101-3. 

 

2017

Sousa S, Duarte AC, Cordeiro I, Ferreira J, Gonçalves MJ, Meirinhos T, Rocha TM, Romão VC, Santos MJ. (2017) Efficacy and Safety of Vaccination in Pediatric Patients with Systemic Inflammatory Rheumatic Diseases: a systematic review of the literature. Acta Reumatol Port 2016; 42: 8-16.

Orr C, Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Le Goff B, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Thurlings R, Fonseca JE, Veale DJ. (2017) Synovial tissue research: a state-of-the-art review. Nat Rev Rheumatol 13:463-475.

Vieira-Sousa E, Cavaleiro J, Mourão AF, Rodrigues AM, Albino-Teixeira A, Pimentel-Santos FM, Oliveira-Ramos F, Canhão H, Polido-Pereira J, Fonseca JE, Pereira da Silva JA, Romeu JC, Melo Gomes J, Costa L, Graça L, Leandro MJ, Santos MJ, Machado PM, Ramiro S. (2017) Acta Reumatológica Portuguesa: perspectives in 2017. Acta Reumatol Port 42:110-111.

Cascão R, Fonseca JE, Moita LF. (2017) Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases. Front Med (Lausanne) 4:69. 

Duarte AC, Santos-Faria D, Gonçalves MJ, Sepriano A, Mourão AF, Duarte C, Neves JS, Águeda AF, Ribeiro PÁ, Daniel A, Neto A, Cordeiro A, Rodrigues A, Barcelos A, Silva C, Ponte C, Vieira-Sousa E, Teixeira F, Oliveira-Ramos F, Araújo F, Barcelos F, Canhão H, Santos H, Ramos J, Pereira J, Costa J, Melo Gomes JA, Cunha-Miranda L, Costa L, Cerqueira M, Cruz M, Santos MJ, Bernardes M, Oliveira P, Abreu P, Figueira R, Barros R, Falcão S, Pinto P, Pimenta S, Capela S, Teixeira V, Fonseca JE. (2017) Portuguese recommendations for the use of methotrexate in rheumatic diseases - 2016 update. Acta Reumatol Port 42: 127-40.

Duarte C, Sousa-Neves J, Águeda A, Ribeiro P, Daniel A, Eugénio G, Serra S, Araújo F, Barcelos A, Filipe B, Bernardes M, Canhão H, Cerqueira M, Capela S, Cordeiro A, Costa F, Costa L, Cruz M, Cunha Miranda L, Duarte C, Falcão S, Faria D, Figueira R, Freitas JP, Gonçalves MJ, Madruga Dias J, Melo Gomes J, Mourão AF, Neto A, Oliveira Ramos F, Pimenta S, Pinto P, Polido Pereira J, Ponte C, Ramos J, Rodrigues A, Santos H, Santos MJ, Sepriano A, Silva C, Tavares Costa J, Teixeira F, Teixeira V, Valente P, Vieira-Sousa E, Barros R, Abreu P, Fonseca JE. (2017) Portuguese Recommendations for the use of biological therapies in patients with rheumatoid arthritis- 2016 update. Acta Reumatol Port 42: 112-26.

van Steenbergen HW, Aletaha D, Beaart-van de Voorde LJ, Brouwer E, Codreanu C, Combe B, Fonseca JE, Hetland ML, Humby F, Kvien TK, Niedermann K, Nuño L, Oliver S, Rantapää-Dahlqvist S, Raza K, van Schaardenburg D, Schett G, De Smet L, Szücs G, Vencovský J, Wiland P, de Wit M, Landewé RL, van der Helm-van Mil AH. (2017) EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis. Ann Rheum Dis 76:491-496. 

Costa N, Marques O, Godinho SI, Carvalho C, Leal B, Figueiredo AM, Vasconcelos C, Marinho A, Moraes-Fontes MF, Gomes da Costa A, Ponte C, Campanilho-Marques R, Cóias T, Martins AR, Viana JF, Lima M, Martins B, Fesel C. (2017) Two separate effects contribute to regulatory T-cell defect in SLE patients and their unaffected relatives. Clin Exp Immunol 189: 318-330.

Germanò G, Monti S, Ponte C, Possemato N, Caporali R, Salvarani C, Macchioni P, Pipitone N. (2017) The role of ultrasound in the diagnosis and follow-up of large-vessel vasculitis: an update. Clin Exp Rheumatol 35 Suppl 103(1):194-198. 

Azevedo V, Hassett B, Fonseca JE, Atsumi T, Coindreau J, Jacobs I, Mahgoub E, O'Brien J, Singh E, Vicik S, Fitzpatrick B. (2017) Differentiating biosimilarity and comparability in biotherapeutics. Clin Rheumatol 35:2877-2886. 

Perpétuo IP, Caetano-Lopes J, Vieira-Sousa E, Campanilho-Marques R, Ponte C, Khmelinskii N, Canhão H, Ainola M, Fonseca JE. (2017) Ankylosing Spondylitis Patients Have Impaired Osteoclast Gene Expression in Circulating Osteoclast Precursors. Front Med 4:38.

Castro AM, Polido-Pereira J, Saraiva F, Pimentao JB, Romeu JC. (2017) Calcium Pyrophosphate Dihydrate Deposition in a Pseudarthrosis. A New Location for an Old Disease. J Clinical Rheumatol 23: 176-178.

Castro A, Romeu JC, Geraldes R, Pereira da Silva JA. (2017) Encephalopathy with upper body hypertonia and myoclonus in a patient with systemic lupus erythematosus and anti-CASPR2. Lupus 26: 84-87.

Cui J, Diogo D, Stahl EA, Canhao H, Mariette X, Greenberg JD, Okada Y, Pappas DA, Fulton RS, Tak PP, Nurmohamed MT, Lee A, Larson DE, Kurreeman F, Deluca TL, O'Laughlin M, Fronick CC, Fulton LL, Mardis ER, van der Horst-Bruinsma IE, Wolbink GJ, Gregersen PK, Kremer JM, Crusius JB, de Vries N, Huizinga TW, Fonseca JE, Miceli-Richard C, Karlson EW, Coenen MJ, Barton A, Plenge RM, Raychaudhuri S. (2017) The role of rare protein-coding variants to anti-TNF treatment response in rheumatoid arthritis. Arthritis Rheumatol 69:735-741. 

Combe B, Landewe R, Daien CI, Hua C, Aletaha D, Álvaro-Gracia JM, Bakkers M, Brodin N, Burmester GR, Codreanu C, Conway R, Dougados M, Emery P, Ferraccioli G, Fonseca J, Raza K, Silva-Fernández L, Smolen JS, Skingle D, Szekanecz Z, Kvien TK, van der Helm-van Mil A, van Vollenhoven R. (2017) 2016 update of the EULAR recommendations for the management of early arthritis. Ann Rheum Dis 76:948-959. 

Steenbergen HW van,  Aletaha D,  van de Voorde LJJB,  Brouwer E,  Codreanu C,  Combe B, Fonseca JE,  Hetland ML,  Humby F, Kvien TK, Niedermann K, Nuño L, Oliver S, Rantapää-Dahlqvist S, Raza K, van Schaardenburg D,  Schett G, De Smet L, Szücs G, Vencovský J, Wiland P, de Wit M, Landewé RL, van der Helm-van Mil AHM. (2017) Extended report: EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis. Ann Rheum Dis 2017 76:491-496. 

Gonçalves MJ, Mourão AF, Martinho A, Simões O, Melo-Gomes J, Salgado M, Estanqueiro P, Ribeiro C, Brito I, Fonseca JE, Canhão H. (2017) Genetic Screening of Mutations Associated with Fabry Disease in a Nationwide Cohort of Juvenile Idiopathic Arthritis Patients. Front Med (Lausanne) 4:12. 

Perpétuo IP, Caetano-Lopes J, Rodrigues AM, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE. (2017) Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Rheumatoid Arthritis. Biomed Res Int 2017:2690402. 

Martins NFE, Seixas MI, Pereira JP, Costa MM, Fonseca JE. (2017)  Anti-müllerian hormone and ovarian reserve in systemic lupus erythematosus. Clin Rheumatol 2017 Aug 22. doi: 10.1007/s10067-017-3797-0. [Epub ahead of print]

Fonseca VR, Agua-Doce A, Maceiras AR, Pierson W, Ribeiro F, Romão VC, Pires AR, da Silva SL, Fonseca JE, Sousa AE, Linterman MA, Graca L. (2017)  Human blood Tfr cells are indicators of ongoing humoral activity not fully licensed with suppressive function. Sci Immunol. 2017 Aug 11;2(14). pii: eaan1487. doi: 10.1126/sciimmunol.aan1487.

Parker LK, Ponte C, Howell KJ, Ong VH, Denton CP, Schreiber BE. (2017) Clinical features and management of erythromelalgia: long term follow-up of 46 cases. Clin Exp Rheumatol 35: 80-84. 

Carvalho PD, Duarte C, Vieira-Sousa E, Cunha-Miranda L, Avila-Ribeiro P, Santos H, Bernardes M, Santos MJ, Cerqueira M, Mateus M, Nero P, Águeda A, Silva JA, Machado P. (2017) Predictors of response to TNF blockers in patients with polyarticular psoriatic arthritis. Acta Reumatol Port 42: 55-65.

Informação atualizada em Agosto de 2017 

 

Documentos

Normas e Procedimentos do Serviço de Reumatologia

Consentimentos Informados 

Folhetos Informativos as Doentes:

Cuidados a ter 48h após o tratamento na Unidade de Técnicas de Reumatologia

Cuidados a ter após procedimento técnico diagnóstico ou terapêutico  

Folheto Artrocentese e sinoviortese do joelho

Folheto Mini-artroscopia do joelho

Folheto Capilaroscopia

Folheto da Biópsia de Gordura Abdominal

Folheto da Densitometria Óssea

Folheto da Fibromialgia

Folheto da Mesoterapia

Folheto das Biópsias guiadas por Ecografia

Folheto de Infiltração Epidural

Folheto de Mesoterapia

Folheto de Recomendações da Biópsia Glândulas Salivares

Folheto Peri-articulares

Folheto Viscossuplementação joelho

Inquérito de satisfação global 

Manual da Artrite Idiopática Juvenil

Manual da Artrite Reumatóide

Manual da Artrite Psoriática

Manual da Espondilite Anquilosante

Manual da Esclerose Sistémica

Manual da Síndrome de Sjogren

Manual do Lupus Eritematoso Sistémico

 

 

Links Úteis

Sociedade Portuguesa de Reumatologia
http://www.spreumatologia.pt/

 

Liga Portuguesa contra as Doenças Reumáticas (LPCDR)

http://www.lpcdr.org.pt

 

Associação Nacional de Doentes com Artrite Reumatóide (ANDAR)

http://www.andar-reuma.pt

 

Associação de Doentes com Lúpus (ADL)

http://www.lupus.pt

 

Associação Nacional de Doentes com Artrite e outros Reumatismos Infantis e Juvenis (ANDAI)

http://www.andai.org.pt

 

Associação Nacional da Espondilite Anquilosante (ANEA)

http://www.anea.org.pt

 

Associação Portuguesa de Osteoporose (APO)

Este endereço de email está protegido contra piratas. Necessita ativar o JavaScript para o visualizar.

 

Associação Nacional Contra a Osteoporose (APOROS)

http://www.aporos.pt

 

Associação Nacional contra a FM e SFC (Myos)

http://www.myos.com.pt

 

Associação Nacional de Doentes com Fibromialgia (APDF)

http://www.apdf.com.pt

 

Associação Portuguesa de Osteogénese Imperfeita

http://apoi.pt/

 

Sociedade Portuguesa de Osteoporose e Doenças Ósseas Metabólicas

http://www.spodom.org